Patch 10.14 is here so lets go over the changes!

Buffs: Alistar, Karthus, Kha’Zix, Riven, Sejuani, Zed

Alistar:
Q – PULVERIZE: CDR

Karthus:
Q – LAY WASTE: 0.35AP Per LVL and now grants 15% damage reduction against Jungle camps
E – DEFILE: Always restores mana both on an off

Kha’Zix:
Q – TASTE THEIR FEAR: Isolated target damage going from 100% to 120%

Riven:
PASSIVE – RUNIC BLADE: 30% to 60% Total attack damage Per LVL
(On hit effects like lifesteal and crit now apply from your spells)

Sejuani:
E – PERMAFROST: Base damage is increased by 15 PER LVL

Zed:
W – LIVING SHADOW: CDR

Nerfs: Ezreal, Pyke, Trundle, Varus, Volibear, Wukong

Ezreal:
E – ARCANE SHIFT: CD Increase

Pyke:
Q – BONE SKEWER: Mana Cost increase, CDR, and 10 damage Per LVL
W – GHOSTWATER DIVE: 40% Movement speed at all ranks
E – PHANTOM UNDERTOW: 10 Damage Per LVL

Trundle:
W – FROZEN DOMAIN: -10% from 20% Bonus attack speed Per LVL

Varus:
Q – PIERCING ARROW: 5% Damage Reduction (Damage reduced to 140% from 150%)
E – HAIL OF ARROWS: Total Base damage -20AD

Volibear: (Base attack speed is now 0.62 from 0.66)
W – FRENZIED MAUL: 50% heal reduced on both minions and monsters

Wukong:
R – CYCLONE: Knock up time is going from 0.75 to 0.60

New: Arcanist Skin line (Zoe, Zoe Prestige, Kog’Maw, Shaco) and Infernal Skin line (Karthus, Vel’Koz, Kennen)

Runes:
Predator- Damage buff from 30DMG-90DMG to now 40DMG-120DMG as well as CDR going from 100s-70s to now 90s-60s
Ghost- Movement speed buff is going from 20%-40% to now 24%-48%

Clash: Conqueror Clash July 11-12

(During this time Challenger and Conqueror skin line is available for purchase in the Riot RP store)

Now lets get into the champion Tier lists
as usual everything is listed in power lvl not alphabetical

Toplane-
S++ / OP Tier: Darius, Quinn, Fiora, Wukong, Garen, Riven
S+ Tier: Volibear, Mordekaiser, Kled, Jax, Urgot, Nasus, Singed, Mowkai
A Tier: Camille, Sett, Renekton, Malphite, Poppy, Vlad, Rengar, Illioai, Teemo, Vayne, Soraka, Tryndamere, Shen, Hecarim, Nautilus
B Tier: Gnar, Pantheon, Kayle, Sion, Kennen, Jayce, Rumble, Gangpank, Sylas, Neeko, Yasuo, Miss Fortune, Lucian, Ornn
C Tier: Aatrox, Dr.Mundo, Zac, Cho’Gath, Ryze
D Tier: Kayn, Akali

Jungle- (As said in previous patches were seeing a rise in AD teams so AP junglers are good right now)
S++ / OP Tier: Fiddlesticks, Nunu
S+ Tier: Volibear, Lee Sin, Rek’Sai, (Leth) Shaco, Elise, Warwick, (Red) Kayne, Evelynn, Nidalee, Wukong, Zac, Graves, Ekko
A Tier: Olaf, (AP) Shyvana, (AD) Shyvana, Kha’Zix, Rengar, Ramus, Kindred, Master Yi, Zin Xho, Vi
B Tier: Amumu, Sejuani, Talyah, Nocturne, Jax, Diana, Morgana, Ivern, Zyra, Dr.Mundo, Udyr, Karthus, Trundle, Twitch
C Tier: Gragus, Pantheon, Skarner, Sett, Sylas
D Tier: Camille, Talon, Zed, Brand, Shen, Teemo, Garen, Darius

Midlane-
S++ / OP Tier: (AP) Kai’sa, Kassadin, Fizz, Vlad, Talon, Cassiopia
S+ Tier: Katarina, Twisted Fate, Ekko, Diana, Zed, Sylas, Galio, Nocturne, Leblanc, Annie
A Tier: Yasuo, Zoe, Ahri, Malzahar, Qiyana, Camille, Aurelion Sol, Neeko, Orianna, Irelia, Lux, Viktor
B Tier: Pantheon, Syndra, Lissandra, Ryze, Vegar, Vel’Koz, Xerath, Rumble, Pyze, Kayle
C Tier: Zigges, Corki, Karma, Anivia, Ornn, Morgana, Sett, Azir
D Tier: Akali, Brand, (AP) Malphite, Zilean

Botlane (Carry)-
S++ / OP Tier: (AP/AS) Kai’sa
S+ Tier: Caitlyn, Draven, Miss Fortune, Jhin
A Tier: Ashe, Sivir, (Healer) Senna, (Healer) Soraka, Vayne, Jinx, Ezreal, Twitch
B Tier: Kog’Maw, Tristana, Lucian, Yasuo, (Leth) Varus, Aphelios, Xayah
C Tier: Kalista, Corki

Botlane (Supports)-
S++ / OP Tier: Sona, Leona, Senna, Soraka, Bard, Lulu, Rakan, Nami, Blitzcrank
S+ Tier: Thresh, Morgana, Janna
A Tier: Yuumi, Karma, Alistar, Pyke, Brand
B Tier: Taric, Vel’Koz, Shaco, Swain, Zyra, Bruam, Lux, Fiddlesticks
C Tier: Xerath, Shen, Poppy
D Tier: Tahm Kench, Volibear

And now for the best runes and items in patch 10.14:
Runes-
Glacial Augment
Dark Harvest / Predator
Guardian
Conqueror

Items-
Death’s Dance & Stromrazor

Champion Tier List compilation came from:
League of Legends, Pro Guide, Challenger Replays, Mobafire, and OP.GG

(Sorry for my lack of posts since patch 10.12)